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Welcome

BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy is a 10-year research programme, co-funded by VINNOVA, University of Gothenburg and 12 other partner organizations.

BIOMATCELL combines the expertise of materials science and medical devices, with state-of-the art and emerging knowledge of biological components, including stem cells, for generating new scientific knowledge, product ideas and clinical therapies in the international fore-front of regenerative medicine. The research profile is truly interdisciplinary, spanning from atomic scale synthesis and characterization of materials, via molecular and cell biology, to the clinical disciplines.

Recent findings and results

Research at BIOMATCELL shows that the presence of nanotopography on a surface can lower the acute inflammatory response from a biomaterial. Activation of the innate immune system was measured in human serum using QCM-D and fluorescence microscopy. Approximately a 50% reduction of the binding of immune complement factor 3 (C3) was found on the nanostructured surfaces. To study the effects of nanotopography, the researchers have developed surfaces that differ only in nanotopography, but not in surface chemistry. This opens new possibilities for the understanding of how proteins, cells and tissue interact with nanostructured biomaterial surfaces.